Calcium-sensing receptors control CYP27B1-luciferase expression. Transcriptional and post-transcriptional mechanisms
نویسندگان
چکیده
منابع مشابه
Post-Transcriptional Control of Chloroplast Gene Expression
Chloroplasts contain their own genome, organized as operons, which are generally transcribed as polycistronic transcriptional units. These primary transcripts are processed into smaller RNAs, which are further modified to produce functional RNAs. The RNA processing mechanisms remain largely unknown and represent an important step in the control of chloroplast gene expression. Such mechanisms in...
متن کاملCalcium inhibits renin gene expression by transcriptional and posttranscriptional mechanisms.
The aim of this study was to investigate the role of cytosolic calcium for renin gene expression in juxtaglomerular cells. For this purpose, we used the immortalized juxtaglomerular mouse cell line As4.1. To increase cytosolic calcium concentration, we treated the cells with thapsigargin and cyclopiazonic acid, inhibitors of the endoplasmatic reticulum Ca- ATPase. Thapsigargin and cyclopiazonic...
متن کاملTranscriptional Control Mechanisms
This text represents the proceedings of a Cetus-UCLA Symposium held in Keystone, Colorado, during April 6-13, 1986, and it contains a diverse selection of the papers presented at the meeting. Much of this work focuses on DNA binding proteins and DNA sequence-specific regulation of gene expression. To illustrate the advances that have been made in this field, the editors have selected many diffe...
متن کاملExpression of oestrogen receptor beta isoforms is regulated by transcriptional and post-transcriptional mechanisms.
Although ERs (oestrogen receptors) mediate breast tumour behaviour, the precise role of ERbeta remains unclear. This is mainly because analyses have been complicated by the presence in breast tissue of three ERbeta protein variants (ERbeta1, ERbeta2 and ERbeta5) that derive from differential 3' splicing. We have recently identified the first known mechanisms responsible for the differential con...
متن کاملClioquinol suppresses cyclin D1 gene expression through transcriptional and post-transcriptional mechanisms.
Clioquinol, a metal-binding compound, has been shown to have anticancer activity in in vitro and in vivo model systems. This study investigated the effects of clioquinol on cyclin D1 gene expression in breast cancer cells. Treatment with clioquinol significantly reduced cyclin D1 protein levels in a concentration-dependent manner, effects being more pronounced in the presence of zinc. Clioquino...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Endocrine Society
سال: 2021
ISSN: 2472-1972
DOI: 10.1210/jendso/bvab057